.SearchBox-module__vLwyuq__searchForm{width:100%;max-width:600px;margin:0 auto}.SearchBox-module__vLwyuq__searchContainer{gap:.5rem;width:100%;display:flex}.SearchBox-module__vLwyuq__searchInput{border:1px solid var(--border-color);border-radius:var(--border-radius);flex:1;padding:.75rem 1rem;font-size:1rem;transition:border-color .2s}.SearchBox-module__vLwyuq__searchInput:focus{border-color:var(--primary-color);outline:none;box-shadow:0 0 0 3px #2563eb1a}.SearchBox-module__vLwyuq__searchButton{background-color:var(--primary-color);color:#fff;border-radius:var(--border-radius);cursor:pointer;border:none;padding:.75rem 1.5rem;font-size:1rem;font-weight:500;transition:background-color .2s}.SearchBox-module__vLwyuq__searchButton:hover{background-color:#1d4ed8}@media (max-width:768px){.SearchBox-module__vLwyuq__searchContainer{flex-direction:column}.SearchBox-module__vLwyuq__searchButton{padding:.75rem}}
.FilterPanel-module__7131qq__filterPanel{border-top:1px solid var(--border-color);padding-top:1.5rem}.FilterPanel-module__7131qq__filterHeader{justify-content:space-between;align-items:center;margin-bottom:1rem;display:flex}.FilterPanel-module__7131qq__filterHeader h3{color:var(--text-color);margin:0;font-size:1rem}.FilterPanel-module__7131qq__filterGrid{grid-template-columns:repeat(auto-fit,minmax(200px,1fr));gap:1rem;display:grid}.FilterPanel-module__7131qq__filterGroup{flex-direction:column;gap:.5rem;display:flex}.FilterPanel-module__7131qq__filterGroup label{color:var(--text-color);font-size:.875rem;font-weight:500}.FilterPanel-module__7131qq__filterSelect{border:1px solid var(--border-color);border-radius:var(--border-radius);background:#fff;padding:.5rem;font-size:.875rem;transition:border-color .2s}.FilterPanel-module__7131qq__filterSelect:focus{border-color:var(--primary-color);outline:none;box-shadow:0 0 0 3px #2563eb1a}@media (max-width:768px){.FilterPanel-module__7131qq__filterGrid{grid-template-columns:1fr}.FilterPanel-module__7131qq__filterHeader{flex-direction:column;align-items:stretch;gap:.5rem}}
.DataTable-module__K4GEfq__tableContainer{max-height:600px;overflow:auto}.DataTable-module__K4GEfq__table{border-collapse:collapse;width:100%;font-size:.875rem}.DataTable-module__K4GEfq__th{background:var(--hover-color);text-align:left;border-bottom:2px solid var(--border-color);color:var(--text-color);z-index:10;padding:.25rem .35rem;font-weight:600;position:sticky;top:0}.DataTable-module__K4GEfq__sortButton{color:var(--text-color);cursor:pointer;text-align:left;background:0 0;border:none;align-items:center;gap:.5rem;width:100%;padding:0;font-size:.875rem;font-weight:600;transition:color .2s;display:flex}.DataTable-module__K4GEfq__sortButton:hover{color:var(--primary-color)}.DataTable-module__K4GEfq__sortIcon{opacity:.7;font-size:.75rem}.DataTable-module__K4GEfq__tr{transition:background-color .2s}.DataTable-module__K4GEfq__tr:hover{background-color:var(--hover-color)}.DataTable-module__K4GEfq__td{border-bottom:1px solid var(--border-color);vertical-align:top;min-width:120px;padding:.25rem .5rem}.DataTable-module__K4GEfq__geneSymbol{color:var(--primary-color);font-weight:600}.DataTable-module__K4GEfq__coordinates{font-family:var(--font-mono),monospace;background:var(--hover-color);color:var(--secondary-color);border-radius:4px;padding:.25rem .5rem;font-size:.8rem}.DataTable-module__K4GEfq__tier{border-radius:4px;padding:.25rem .5rem;font-size:.75rem;font-weight:500}.DataTable-module__K4GEfq__tier1{color:#166534;background-color:#dcfce7}.DataTable-module__K4GEfq__tier2{color:#166534;background-color:#c2f6d5}.DataTable-module__K4GEfq__tier3{color:#92400e;background-color:#fef3c7}.DataTable-module__K4GEfq__tier4{color:#92400e;background-color:#ebe1b9}.DataTable-module__K4GEfq__tier5,.DataTable-module__K4GEfq__tier6,.DataTable-module__K4GEfq__tier7{color:#fffdff;background-color:#6c9fec}.DataTable-module__K4GEfq__variantType{font-family:var(--font-mono),monospace;background:var(--hover-color);border-radius:4px;padding:.25rem .5rem;font-size:.8rem}.DataTable-module__K4GEfq__pValue{font-family:var(--font-mono),monospace;color:var(--secondary-color);font-size:.8rem}.DataTable-module__K4GEfq__reference{color:var(--secondary-color);font-size:.8rem}.DataTable-module__K4GEfq__emptyState{text-align:center;color:var(--secondary-color);padding:3rem}.DataTable-module__K4GEfq__tableHeader{border-bottom:1px solid var(--border-color);flex-wrap:wrap;justify-content:space-between;align-items:center;gap:1rem;margin-bottom:1rem;padding:1rem 0;display:flex}.DataTable-module__K4GEfq__stats{color:var(--secondary-color);gap:1.5rem;font-size:.875rem;display:flex}.DataTable-module__K4GEfq__duplicateWarning{color:var(--warning-color);font-weight:500}.DataTable-module__K4GEfq__viewToggle{align-items:center;display:flex}.DataTable-module__K4GEfq__toggleLabel{color:var(--text-color);cursor:pointer;align-items:center;gap:.5rem;font-size:.875rem;display:flex}.DataTable-module__K4GEfq__toggleInput{width:1rem;height:1rem;accent-color:var(--primary-color)}.DataTable-module__K4GEfq__entryCount{color:var(--secondary-color);margin-left:.5rem;font-size:.75rem;font-weight:400}.DataTable-module__K4GEfq__viewMoreBtn{color:var(--primary-color);cursor:pointer;background:0 0;border:none;margin-left:.5rem;font-size:.75rem}.DataTable-module__K4GEfq__viewMoreBtn:hover{text-decoration:underline}.DataTable-module__K4GEfq__expandedList{color:var(--secondary-color);white-space:normal;max-height:120px;margin-top:.25rem;font-size:.75rem;line-height:1.4;overflow-y:auto}.DataTable-module__K4GEfq__colPhenotypes{white-space:normal;word-break:break-word;min-width:150px}.DataTable-module__K4GEfq__colNearbyGenes{white-space:normal;word-break:break-word;min-width:160px}.DataTable-module__K4GEfq__link{color:var(--primary-color);font-weight:500;text-decoration:none}.DataTable-module__K4GEfq__link:hover{text-decoration:underline}@media (max-width:768px){.DataTable-module__K4GEfq__table{font-size:.8rem}.DataTable-module__K4GEfq__th,.DataTable-module__K4GEfq__td{padding:.5rem}.DataTable-module__K4GEfq__sortButton{font-size:.8rem}.DataTable-module__K4GEfq__coordinates,.DataTable-module__K4GEfq__variantType,.DataTable-module__K4GEfq__pValue{font-size:.75rem}.DataTable-module__K4GEfq__tableHeader{flex-direction:column;align-items:flex-start}.DataTable-module__K4GEfq__stats{flex-direction:column;gap:.5rem}}
.LoadingSpinner-module__D6aYqa__container{flex-direction:column;justify-content:center;align-items:center;padding:2rem;display:flex}.LoadingSpinner-module__D6aYqa__spinner{border:3px solid var(--border-color);border-top:3px solid var(--primary-color);border-radius:50%;animation:1s linear infinite LoadingSpinner-module__D6aYqa__spin}.LoadingSpinner-module__D6aYqa__small{border-width:2px;width:20px;height:20px}.LoadingSpinner-module__D6aYqa__medium{width:40px;height:40px}.LoadingSpinner-module__D6aYqa__large{border-width:4px;width:60px;height:60px}.LoadingSpinner-module__D6aYqa__message{color:var(--secondary-color);margin-top:1rem;font-size:.875rem}@keyframes LoadingSpinner-module__D6aYqa__spin{0%{transform:rotate(0)}to{transform:rotate(360deg)}}
.page-module__E0kJGG__container{max-width:var(--container-max-width);margin:0 auto;padding:2rem 1rem}.page-module__E0kJGG__hero{text-align:center;margin-bottom:3rem}.page-module__E0kJGG__title{color:var(--text-color);margin-bottom:.5rem;font-size:2.5rem;font-weight:700;line-height:1.2}.page-module__E0kJGG__subtitle{color:var(--secondary-color);margin-top:.5rem;font-size:1.5rem;font-weight:400;display:block}.page-module__E0kJGG__description{color:var(--secondary-color);max-width:800px;margin:1.5rem auto 0;font-size:1.125rem;line-height:1.7}.page-module__E0kJGG__info{color:var(--text-color);background-color:var(--hover-color);max-width:800px;margin:3.5rem auto 0;padding:1.5rem;font-size:1.25rem;font-style:italic}.page-module__E0kJGG__searchSection{border-radius:var(--border-radius);box-shadow:var(--shadow);text-align:center;background:#fff;margin-bottom:3rem;padding:2rem}.page-module__E0kJGG__searchSection h2{color:var(--text-color);margin-bottom:1rem}.page-module__E0kJGG__searchHint{color:var(--secondary-color);margin-top:.5rem;font-size:.875rem}.page-module__E0kJGG__searchResults{text-align:left;margin-top:2rem}.page-module__E0kJGG__errorMessage{color:#dc2626;border-radius:var(--border-radius);text-align:center;background-color:#fef2f2;border:1px solid #fecaca;padding:1rem}.page-module__E0kJGG__ideogramPlaceholder{margin-bottom:3rem}.page-module__E0kJGG__ideogramPlaceholder h3{color:var(--text-color);margin-bottom:1rem}.page-module__E0kJGG__placeholder{background:var(--hover-color);border:2px dashed var(--border-color);border-radius:var(--border-radius);text-align:center;padding:3rem}.page-module__E0kJGG__placeholderText{color:var(--secondary-color);margin-top:.5rem;font-size:.875rem}.page-module__E0kJGG__quickActions{margin-bottom:3rem}.page-module__E0kJGG__quickActions h3{color:var(--text-color);margin-bottom:1.5rem}.page-module__E0kJGG__actionGrid{grid-template-columns:repeat(auto-fit,minmax(280px,1fr));gap:1.5rem;display:grid}.page-module__E0kJGG__actionCard{border:1px solid var(--border-color);border-radius:var(--border-radius);color:var(--text-color);box-shadow:var(--shadow);background:#fff;padding:1.5rem;text-decoration:none;transition:all .2s}.page-module__E0kJGG__actionCard:hover{border-color:var(--primary-color);transform:translateY(-2px);box-shadow:0 4px 12px #00000026}.page-module__E0kJGG__actionCard h4{color:var(--primary-color);margin-bottom:.5rem;font-size:1.125rem}.page-module__E0kJGG__actionCard p{color:var(--secondary-color);font-size:.875rem;line-height:1.5}.page-module__E0kJGG__acknowledgements{border-radius:var(--border-radius);text-align:center;padding:2rem}.page-module__E0kJGG__acknowledgements h3{color:var(--text-color);margin-bottom:1rem}.page-module__E0kJGG__acknowledgements p{color:var(--secondary-color);text-align:left;max-width:800px;margin:0 auto;line-height:1.7}@media (max-width:768px){.page-module__E0kJGG__container{padding:1rem}.page-module__E0kJGG__title{font-size:2rem}.page-module__E0kJGG__subtitle{font-size:1.25rem}.page-module__E0kJGG__description{font-size:1rem}.page-module__E0kJGG__searchSection{padding:1.5rem}.page-module__E0kJGG__actionGrid{grid-template-columns:1fr}.page-module__E0kJGG__acknowledgements{padding:1.5rem}}
.page-module__oVlIsW__container{max-width:var(--container-max-width);margin:0 auto;padding:2rem 1rem}.page-module__oVlIsW__header{text-align:center;margin-bottom:2rem}.page-module__oVlIsW__header h1{color:var(--text-color);margin-bottom:.5rem;font-size:2rem}.page-module__oVlIsW__header p{color:var(--secondary-color);max-width:600px;margin:0 auto;font-size:1rem}.page-module__oVlIsW__controls{border:1px solid var(--border-color);border-radius:var(--border-radius);box-shadow:var(--shadow);background:#fff;margin-bottom:2rem;padding:1.5rem}.page-module__oVlIsW__searchSection{margin-bottom:1.5rem}.page-module__oVlIsW__resetSection{justify-content:flex-end;margin-top:1rem;display:flex}.page-module__oVlIsW__resetButton{background:var(--error-color);color:#fff;border-radius:var(--border-radius);cursor:pointer;border:none;align-self:flex-start;padding:.5rem 1rem;font-size:.875rem;font-weight:500;transition:background-color .2s}.page-module__oVlIsW__resetButton:hover{background:#b91c1c}.page-module__oVlIsW__clearButton{border:1px solid var(--border-color);color:var(--secondary-color);border-radius:var(--border-radius);cursor:pointer;background:0 0;padding:.25rem .75rem;font-size:.875rem;transition:all .2s}.page-module__oVlIsW__clearButton:hover{background:var(--hover-color);border-color:var(--primary-color);color:var(--primary-color)}.page-module__oVlIsW__resultsSection{border:1px solid var(--border-color);border-radius:var(--border-radius);box-shadow:var(--shadow);background:#fff;overflow:hidden}.page-module__oVlIsW__resultsHeader{background:var(--hover-color);border-bottom:1px solid var(--border-color);flex-wrap:wrap;justify-content:space-between;align-items:center;gap:1rem;padding:1rem 1.5rem;display:flex}.page-module__oVlIsW__resultsInfo{color:var(--secondary-color);font-size:.875rem}.page-module__oVlIsW__actions{align-items:center;gap:1rem;display:flex}.page-module__oVlIsW__pageSizeSelect{border:1px solid var(--border-color);border-radius:var(--border-radius);background:#fff;padding:.5rem;font-size:.875rem}.page-module__oVlIsW__exportButton{background-color:var(--success-color);color:#fff;border-radius:var(--border-radius);cursor:pointer;border:none;padding:.5rem 1rem;font-size:.875rem;font-weight:500;transition:background-color .2s}.page-module__oVlIsW__exportButton:hover{background-color:#047857}.page-module__oVlIsW__pagination{background:var(--hover-color);border-top:1px solid var(--border-color);justify-content:center;align-items:center;gap:.5rem;padding:1rem;display:flex}.page-module__oVlIsW__pageNumbers{gap:.25rem;display:flex}.page-module__oVlIsW__pageButton{border:1px solid var(--border-color);color:var(--text-color);border-radius:var(--border-radius);cursor:pointer;background:#fff;padding:.5rem .75rem;font-size:.875rem;transition:all .2s}.page-module__oVlIsW__pageButton:hover:not(:disabled){background:var(--hover-color);border-color:var(--primary-color)}.page-module__oVlIsW__pageButton:disabled{opacity:.5;cursor:not-allowed}.page-module__oVlIsW__activePage{background-color:var(--primary-color);color:#fff;border-color:var(--primary-color)}.page-module__oVlIsW__errorMessage{text-align:center;border:1px solid var(--border-color);border-radius:var(--border-radius);background:#fff;padding:3rem}.page-module__oVlIsW__errorMessage h2{color:var(--error-color);margin-bottom:1rem}.page-module__oVlIsW__errorMessage p{color:var(--secondary-color)}.page-module__oVlIsW__columnMenuWrapper{position:relative}.page-module__oVlIsW__columnMenuButton{border:1px solid var(--border-color);border-radius:var(--border-radius);cursor:pointer;background:#fff;padding:.5rem .75rem;font-size:.875rem;transition:background .2s}.page-module__oVlIsW__columnMenuButton:hover{background:var(--hover-color)}.page-module__oVlIsW__columnMenu{border:1px solid var(--border-color);border-radius:var(--border-radius);box-shadow:var(--shadow);z-index:20;white-space:nowrap;background:#fff;flex-direction:column;gap:.5rem;min-width:220px;max-height:300px;padding:.75rem;display:flex;position:absolute;top:110%;right:0;overflow-y:auto}.page-module__oVlIsW__toggleLabel{cursor:pointer;color:var(--text-color);align-items:center;gap:.5rem;font-size:.875rem;display:flex}.page-module__oVlIsW__toggleInput{width:1rem;height:1rem;accent-color:var(--primary-color)}@media (max-width:768px){.page-module__oVlIsW__container{padding:1rem}.page-module__oVlIsW__header h1{font-size:1.5rem}.page-module__oVlIsW__controls{padding:1rem}.page-module__oVlIsW__resultsHeader{flex-direction:column;align-items:stretch;gap:1rem}.page-module__oVlIsW__actions{flex-direction:column;align-items:stretch}.page-module__oVlIsW__pagination{flex-wrap:wrap;gap:.25rem}.page-module__oVlIsW__pageNumbers{order:-1;justify-content:center;width:100%}}